In the 1800s, a surgeon named Edward Jukes came up with the technique of gastric lavage (stomach pumping). He demonstrated the efficacy of the technique by intentionally overdosing on laudanum, which contains morphine and codeine, then having his stomach washed out. He survived to write a somewhat strange book (for example, he recommended gastric lavage as a treatment for women who were prone to miscarriage).
I learned this from The Courageous - and Weird - Tradition of Self-Experimentation.
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